Description
Product Characteristics:
Aliases: Antizyme 3 antibody, AZ3 antibody, OAZ t antibody, OAZ3 antibody, OAZ3_HUMAN antibody, ODC-Az 3 antibody, Ornithine decarboxylase antizyme 3 antibody, RP11-98D18.13-004 antibody, Testicular secretory protein Li 31 antibody, TISP15 antibody
Target Information: Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. In contrast to antizymes 1 and 2, which are widely expressed throughout the body, the expression of this gene product (antizyme 3) is restricted to testis germ cells, and thus it is a possible candidate for heritable forms of human male infertility. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]